Chronic Low-Dose Cadmium Exposure Impairs Cutaneous Wound Healing With Defective Early Inflammatory Responses After Skin Injury

Hong, Mei; Yao, Pengle; Wang, Shanshan; Li, Na; Zhu, Tengfei; Chen, Xiaofang; Yang, Mengmei; Zhuo, Shu; Chen, Shiting; Ming Wang, Ji; Wang, Hui; Xie, Dong; Wu, Yongning; Le, Yingying

doi:10.1093/toxsci/kfx137

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Chronic Low-Dose Cadmium Exposure Impairs Cutaneous Wound Healing With Defective Early Inflammatory Responses After Skin Injury

Published in Toxicological Sciences • Jun 28, 2017

Authors:

Mei Hong

Pengle Yao

Shanshan Wang

Abstract

Impairment of the immune system is a developing concern in evaluating the toxicity of cadmium (Cd). In the present study, we investigated if Cd could impair cutaneous wound healing through interfering with inflammation after injury. We found that exposure of mice to CdCl2 through drinking water at d...

Subject

Proinflammatory cytokine

Chemokine

CXCL1

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