Epigenome‐wide association of PTSD from heterogeneous cohorts with a common multi‐site analysis pipeline

Ratanatharathorn, Andrew; P. Boks, Marco; X. Maihofer, Adam; E. Aiello, Allison; B. Amstadter, Ananda; E. Ashley‐Koch, Allison; G. Baker, Dewleen; C. Beckham, Jean; J. Bromet, Evelyn; F. Dennis, Michelle; E. Garrett, Melanie; Geuze, Elbert; Guffanti, Guia; A. Hauser, Michael; Kilaru, Varun; A. Kimbrel, Nathan; C. Koenen, Karestan; Fen Kuan, Pei; W. Logue, Mark; J. Luft, Benjamin; W. Miller, Mark; Mitchell, Colter; R. Nugent, Nicole; J. Ressler, Kerry; P. F. Rutten, Bart; B. Stein, Murray; Vermetten, Eric; H. Vinkers, Christiaan; A. Youssef, Nagy; Mid‐Atlantic MIRECC Workgroup, VA; PTSD Epigenetics Workgroup, PGC; Uddin, Monica; M. Nievergelt, Caroline; K. Smith, Alicia

doi:10.1002/ajmg.b.32568

Public

Epigenome‐wide association of PTSD from heterogeneous cohorts with a common multi‐site analysis pipeline

Published in American Journal of Medical Genetics Part B Neuropsychiatric Genetics • Jul 10, 2017

Authors:

Andrew Ratanatharathorn

Marco P. Boks

Adam X. Maihofer

Abstract

Compelling evidence suggests that epigenetic mechanisms such as DNA methylation play a role in stress regulation and in the etiologic basis of stress related disorders such as Post traumatic Stress Disorder (PTSD). Here we describe the purpose and methods of an international consortium that was deve...

Subject

DNA methylation

Population stratification

Epigenetics

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