Continuous O2-Evolving MnFe2O4 Nanoparticle-Anchored Mesoporous Silica Nanoparticles for Efficient Photodynamic Therapy in Hypoxic Cancer

Kim, Jonghoon; Rim Cho, Hye; Jeon, Hyejin; Kim, Dokyoon; Song, Changyeong; Lee, Nohyun; Hong Choi, Seung; Hyeon, Taeghwan

doi:10.1021/jacs.7b05559

Public

Continuous O2-Evolving MnFe2O4 Nanoparticle-Anchored Mesoporous Silica Nanoparticles for Efficient Photodynamic Therapy in Hypoxic Cancer

Published in Journal of the American Chemical Society • Jul 24, 2017

Authors:

Jonghoon Kim

Hye Rim Cho

Hyejin Jeon

Abstract

Therapeutic effects of photodynamic therapy (PDT) are limited by cancer hypoxia because the PDT process is dependent on O 2 concentration. Herein, we design biocompatible manganese ferrite nanoparticle-anchored mesoporous silica nanoparticles (MFMSNs) to overcome hypoxia, consequently enhancing the ...

Subject

Mesoporous silica

Photodynamic therapy

Nanoparticle

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