Different Potential of Extracellular Vesicles to Support Thrombin Generation: Contributions of Phosphatidylserine, Tissue Factor, and Cellular Origin

Tripisciano, Carla; Weiss, René; Eichhorn, Tanja; Spittler, Andreas; Heuser, Thomas; B. Fischer, Michael; Weber, Viktoria

doi:10.1038/s41598-017-03262-2

Public

Different Potential of Extracellular Vesicles to Support Thrombin Generation: Contributions of Phosphatidylserine, Tissue Factor, and Cellular Origin

Published in Scientific Reports • Jul 20, 2017

Authors:

Carla Tripisciano

René Weiss

Tanja Eichhorn

Abstract

Cells release diverse types of vesicles constitutively or in response to proliferation, injury, inflammation, or stress. Extracellular vesicles (EVs) are crucial in intercellular communication, and there is emerging evidence for their roles in inflammation, cancer, and thrombosis. We investigated th...

Subject

Tissue factor

Phosphatidylserine

Thrombogenicity

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