Prophylactic Treatment with Cerium Oxide Nanoparticles Attenuate Hepatic Ischemia Reperfusion Injury in Sprague Dawley Rats

D.P.K. Manne, Nandini; Arvapalli, Ravikumar; Graffeo, Vincent; Vinay Kumar Bandarupalli, Venkata; Shokuhfar, Tolou; Patel, Sweetu; M. Rice, Kevin; K. Ginjupalli, Gautam; R. Blough, Eric

doi:10.1159/000479540

Public

Prophylactic Treatment with Cerium Oxide Nanoparticles Attenuate Hepatic Ischemia Reperfusion Injury in Sprague Dawley Rats

Published in Cellular Physiology and Biochemistry • Jan 1, 2017

Authors:

Nandini D.P.K. Manne

Ravikumar Arvapalli

Vincent Graffeo

Abstract

BACKGROUND: Hepatic ischemia reperfusion is one the main causes for graft failure following transplantation. Although, the molecular events that lead to hepatic failure following ischemia reperfusion (IR) are diverse and complex, previous studies have shown that excessive formation of reactive oxyge...

Subject

Reperfusion injury

Ischemia

Pharmacology

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