Separate and combined associations of obesity and metabolic health with coronary heart disease: a pan-European case-cohort analysis

Lassale, Camille; Tzoulaki, Ioanna; G.M. Moons, Karel; Sweeting, Michael; M.A. Boer, Jolanda; Johnson, Laura; María Huerta, José; Agnoli, Claudia; Freisling, Heinz; Weiderpass, Elisabete; Wennberg, Patrik; L. van der A, Daphne; Arriola, Larraitz; Benetou, Vassiliki; Boeing, Heiner; Bonnet, Fabrice; M. Colorado‐Yohar, Sandra; Engström, Gunnar; Kirstine Eriksen, Anne; Ferrari, Pietro; Grioni, Sara; Johansson, Matthias; Kaaks, Rudolf; Katsoulis, Michail; Katzke, Verena; J. Key, Timothy; Matullo, Giuseppe; Melander, Olle; Molina‐Portillo, Elena; Moreno-Iribas, Concepción; Norberg, Margareta; Overvad, Kim; Panico, Salvatore; Ramón Quirós, J.; Saieva, Calogero; Skeie, Guri; Steffen, Annika; Stępień, Magdalena; Tjønneland, Anne; Trichopoulou, Antonia; ­Tumino, ­Rosario; T. van der Schouw, Yvonne; M. Monique Verschuren, W.; Langenberg, Claudia; Di Angelantonio, Emanuele; Ríboli, Elio; J. Wareham, Nicholas; Danesh, John; S. Butterworth, Adam

doi:10.1093/eurheartj/ehx448

Public

Separate and combined associations of obesity and metabolic health with coronary heart disease: a pan-European case-cohort analysis

Published in European Heart Journal • Jul 18, 2017

Authors:

Camille Lassale

Ioanna Tzoulaki

Karel G.M. Moons

Abstract

Aims: The hypothesis of 'metabolically healthy obesity' implies that, in the absence of metabolic dysfunction, individuals with excess adiposity are not at greater cardiovascular risk. We tested this hypothesis in a large pan-European prospective study. Methods and results: We conducted a case-cohor...

Subject

Medicine

Obesity

Coronary heart disease

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