Pathogen reduction through additive-free short-wave UV light irradiation retains the optimal efficacy of human platelet lysate for the expansion of human bone marrow mesenchymal stem cells

Viau, Sabrina; Chabrand, Lucie; Eap, Sandy; Lorant, Judith; Rouger, Karl; Goudaliez, F.; Sumian, Chryslain; Delorme, Bruno

doi:10.1371/journal.pone.0181406

Public

Pathogen reduction through additive-free short-wave UV light irradiation retains the optimal efficacy of human platelet lysate for the expansion of human bone marrow mesenchymal stem cells

Published in PLoS ONE • Aug 1, 2017

Authors:

Sabrina Viau

Lucie Chabrand

Sandy Eap

Abstract

BACKGROUND: We recently developed and characterized a standardized and clinical grade human Platelet Lysate (hPL) that constitutes an advantageous substitute for fetal bovine serum (FBS) for human mesenchymal stem cell (hMSC) expansion required in cell therapy procedures, avoiding xenogenic risks (v...

Subject

Mesenchymal stem cell

Platelet lysate

Platelet

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