Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation

Tzannou, Ifigeneia; Παπαδοπούλου, Αναστασία; Naik, Swati; Leung, Kathryn; Martinez, Caridad; A. Ramos, Carlos; Carrum, George; Sasa, Ghadir; Lulla, Premal; Watanabe, Ayumi; Kuvalekar, Manik; P. Gee, Adrian; Wu, Meng-Fen; Liu, Hao; Grilley, Bambi; A. Krance, Robert; Gottschalk, Stephen; K. Brenner, Malcolm; M. Rooney, Cliona; E. Heslop, Helen; M. Leen, Ann; Omer, Bilal

doi:10.1200/jco.2017.73.0655

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Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation

Published in Journal of Clinical Oncology • Aug 7, 2017

Authors:

Ifigeneia Tzannou

Αναστασία Παπαδοπούλου

Swati Naik

Abstract

Purpose Improvement of cure rates for patients treated with allogeneic hematopoietic stem-cell transplantation (HSCT) will require efforts to decrease treatment-related mortality from severe viral infections. Adoptively transferred virus-specific T cells (VSTs) generated from eligible, third-party d...

Subject

Medicine

BK virus

Hemorrhagic cystitis

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