Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease

Neu, Scott; Pa, Judy; A. Kukull, Walter; Beekly, Duane; Kuzma, Amanda; Gangadharan, Prabhakaran; Wang, Li-San; Romero, Klaus; P. Arnerić, Stephen; Redolfi, Alberto; Orlandi, Daniele; B. Frisoni, Giovanni; Au, Rhoda; Devine, Sherral; Auerbach, Sanford; Espinosa, Ana; Boada, Merçé; Ruiz, Agustı́n; C. Johnson, Sterling; L. Koscik, Rebecca; Wang, Jiun‐Jie; Hsu, Wen‐Chuin; Chen, Yao-Liang; W. Toga, Arthur

doi:10.1001/jamaneurol.2017.2188

Public

Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease

Published in JAMA Neurology • Aug 28, 2017

Authors:

Scott Neu

Judy Pa

Walter A. Kukull

Abstract

Importance: It is unclear whether female carriers of the apolipoprotein E (APOE) ε4 allele are at greater risk of developing Alzheimer disease (AD) than men, and the sex-dependent association of mild cognitive impairment (MCI) and APOE has not been established. Objective: To determine how sex and AP...

Subject

Apolipoprotein E

Odds ratio

Demography

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