Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection

T. Schooley, Robert; Biswas, Biswajit; J. Gill, Jason; Hernandez-Morales, Adriana; Lancaster, Jacob; Lessor, Lauren; J. Barr, Jeremy; L. Reed, Sharon; Rohwer, Forest; Benler, Sean; M. Segall, Anca; Taplitz, Randy; M. Smith, Davey; M. Kerr, Kim; Kumaraswamy, Monika; Nizet, Victor; Lin, Leo; McCauley, Melanie; A. Strathdee, Steffanie; A. Benson, Constance; K. Pope, Robert; M. Leroux, Brian; C. Picel, Andrew; Mateczun, Alfred; E. Cilwa, Katherine; Regeimbal, James; A. Estrella, Luis; M. Wolfe, David; S. Henry, Matthew; Quiñónes, Javier; Salka, Scott; A. Bishop‐Lilly, Kimberly; Young, Ry; Hamilton, Theron

doi:10.1128/aac.00954-17

Public

Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection

Published in Antimicrobial Agents and Chemotherapy • Aug 14, 2017

Authors:

Robert T. Schooley

Biswajit Biswas

Jason J. Gill

Abstract

ABSTRACT Widespread antibiotic use in clinical medicine and the livestock industry has contributed to the global spread of multidrug-resistant (MDR) bacterial pathogens, including Acinetobacter baumannii . We report on a method used to produce a personalized bacteriophage-based therapeutic treatment...

Subject

Acinetobacter baumannii

Lytic cycle

Antibiotics

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