Ten-year follow-up of human papillomavirus vaccine efficacy against the most stringent cervical neoplasia end-point—registry-based follow-up of three cohorts from randomized trials

Lehtinen, Matti; Lagheden, Camilla; Luostarinen, Tapio; Eriksson, Tiina; Apter, Dan; Harjula, Katja; Kuortti, Marjo; Natunen, Kari; Palmroth, Johanna; Petäjä, Tiina; Pukkala, ­Eero; Siitari‐Mattila, Mari; Struyf, Frank; Nieminen, Pekka; Paavonen, Jorma; Dubin, Gary; Dillner, Joakim

doi:10.1136/bmjopen-2017-015867

Public

Ten-year follow-up of human papillomavirus vaccine efficacy against the most stringent cervical neoplasia end-point—registry-based follow-up of three cohorts from randomized trials

Published in BMJ Open • Aug 1, 2017

Authors:

Matti Lehtinen

Camilla Lagheden

Tapio Luostarinen

Abstract

OBJECTIVE: Due to long lag time between infection/cancer diagnoses human papillomavirus (HPV) vaccination programs will deliver vaccine efficacy (VE) estimates against cancer end-points late. Cancer registry follow-up of population-based, randomised trial cohorts of vaccinated and unvaccinated women...

Subject

Medicine

Cervical intraepithelial neoplasia

Cervical cancer

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