VDJdb: a curated database of T-cell receptor sequences with known antigen specificity.

Shugay, Mikhail; V Bagaev, Dmitriy; V Zvyagin, Ivan; M Vroomans, Renske; Chase Crawford, Jeremy; Dolton, Garry; A Komech, Ekaterina; L Sycheva, Anastasiya; E Koneva, Anna; S Egorov, Evgeniy; V Eliseev, Alexey; Van Dyk, Ewald; Dash, Pradyot; Attaf, Meriem; Rius, Cristina; Ladell, Kristin; E McLaren, James; K Matthews, Katherine; Bridie Clemens, E; C Douek, Daniel; Luciani, Fabio; van Baarle, Debbie; Kedzierska, Katherine; Kesmir, Can; G Thomas, Paul; A Price, David; K Sewell, Andrew; M Chudakov, Dmitriy

doi:10.1093/nar/gkx760

Public

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity.

Published in Nucleic acids research • Jan 4, 2018

NobleIDark:/48914/w1/20260526/9B632CD4Record on NobleID

Authors:

Mikhail Shugay

,

Dmitriy V Bagaev

,

Ivan V Zvyagin

Abstract

The ability to decode antigen specificities encapsulated in the sequences of rearranged T-cell receptor (TCR) genes is critical for our understanding of the adaptive immune system and promises significant advances in the field of translational medicine. Recent developments in high-throughput sequenc...

Discussions