Circular Noncoding RNA HIPK3 Mediates Retinal Vascular Dysfunction in Diabetes Mellitus

Y. Shan, K.; Liu, Chang; Liu, Bai-Hui; Chen, Xue; Dong, Rui; Liu, Xin; Zhang, Yangyang; Liu, Ban; Zhang, Shujie; Wang, Jiajian; Zhang, Sheng-Hai; Wu, Jihong; Zhao, Chen; Yan, Biao

doi:10.1161/circulationaha.117.029004

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Circular Noncoding RNA HIPK3 Mediates Retinal Vascular Dysfunction in Diabetes Mellitus

Published in Circulation • Sep 1, 2017

Authors:

K. Y. Shan

Chang Liu

Bai-Hui Liu

Abstract

BACKGROUND: The vascular complications of diabetes mellitus are the major causes of morbidity and mortality among people with diabetes. Circular RNAs are a class of endogenous noncoding RNAs that regulate gene expression in eukaryotes. In this study, we investigated the role of circular RNA in retin...

Subject

Retinal

Diabetes mellitus

Gene silencing

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