Enhanced Photobactericidal and Targeting Properties of a Cationic Porphyrin following the Attachment of Polymyxin B

Le Guern, Florent; Sol, Vincent; Ouk, Catherine; Arnoux, Philippe; Frochot, Céline; Ouk, Tan‐Sothéa

doi:10.1021/acs.bioconjchem.7b00516

Public

Enhanced Photobactericidal and Targeting Properties of a Cationic Porphyrin following the Attachment of Polymyxin B

Published in Bioconjugate Chemistry • Aug 30, 2017

Authors:

Florent Le Guern

Vincent Sol

Catherine Ouk

Abstract

A novel compound consisting of a cationic porphyrin covalently attached to a derivative of polymyxin B has been synthesized and presents enhanced activity and targeting properties compared to the usual cationic porphyrins recognized as efficient photosensitizers in photodynamic antimicrobial chemoth...

Subject

Chemistry

Cationic polymerization

Porphyrin

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