The RNA m 6 A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence

YTHDF2 binds and destabilizes N 6 -methyladenosine (m 6 A)-modified mRNA. The extent to which this branch of m 6 A RNA-regulatory pathway functions in vivo and contributes to mammalian development remains unknown. Here we find that YTHDF2 deficiency is partially permissive in mice and results in fem... View More