Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes

R. Holman, Rury; Angelyn Bethel, M.; J. Mentz, Robert; P. Thompson, Vivian; Lokhnygina, Yuliya; B. Buse, John; C.N. Chan, Juliana; Choi, Jasmine; M. Gustavson, Stephanie; Iqbal, Nayyar; P. Maggioni, Aldo; P. Marso, Steven; Öhman, Peter; J. Pagidipati, Neha; R Poulter, Neil; Ramachandran, Ambady; Zinman, Bernard; F. Hernandez, Adrian

doi:10.1056/nejmoa1612917

Public

Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes

Published in New England Journal of Medicine • Sep 14, 2017

Authors:

Rury R. Holman

M. Angelyn Bethel

Robert J. Mentz

Abstract

BACKGROUND: The cardiovascular effects of adding once-weekly treatment with exenatide to usual care in patients with type 2 diabetes are unknown. METHODS: We randomly assigned patients with type 2 diabetes, with or without previous cardiovascular disease, to receive subcutaneous injections of extend...

Subject

Medicine

Exenatide

Hazard ratio

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