Genistein suppresses aerobic glycolysis and induces hepatocellular carcinoma cell death.

Sainan, Li,; Jingjing, Li,; Weiqi, Dai,; Qinghui, Zhang,; Jiao, Feng,; Liwei, Wu,; Tong, Liu,; Qiang, Yu,; Shizan, Xu,; Wenwen, Wang,; Xiya, Lu,; Kan, Chen,; Yujing, Xia,; Jie, Lu,; Yingqun, Zhou,; Xiaoming, Fan,; Wenhui, Mo,; Ling, Xu,; Chuanyong, Guo,

doi:10.1038/bjc.2017.323

Public

Genistein suppresses aerobic glycolysis and induces hepatocellular carcinoma cell death.

Published in British journal of cancer • Nov 7, 2017

Authors:

Li, Sainan

Li, Jingjing

Dai, Weiqi

Abstract

BACKGROUND: Genistein is a natural isoflavone with many health benefits, including antitumour effects. Increased hypoxia-inducible factor 1 α (HIF-1α) levels and glycolysis in tumour cells are associated with an increased risk of mortality, cancer progression, and resistance to therapy. However, the...

Subject

Animals

Antineoplastic Agents

Apoptosis

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!