Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study

Bergsten, Elisabet; Horne, AnnaCarin; Aricò, Maurizio; Astigarraga, Itziar; Maarten Egeler, R.; H. Filipovich, Alexandra; Ishii, Eiichi; Janka, Gritta; Ladisch, Stephan; Lehmberg, Kai; L. McClain, Kenneth; Minkov, Milen; Montgomery, Scott; Nanduri, Vasanta; Rosso, Diego; Henter, Jan‐Inge

doi:10.1182/blood-2017-06-788349

Public

Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study

Published in Blood • Sep 21, 2017

Authors:

Elisabet Bergsten

AnnaCarin Horne

Maurizio Aricò

Abstract

020 adjusted for age and sex) and reported neurological alterations at HSCT were 22% in HLH-94 and 17% in HLH-2004 (using HLH-94 inclusion criteria). Five-year pSu post-HSCT overall was 66% (verified FHL, 70% [63%-78%]). Additional analyses provided specific suggestions on potential pre-HSCT treatme...

Subject

Etoposide

Dexamethasone

Hemophagocytic lymphohistiocytosis

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