The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6

Yin, Yuan; Yao, Surui; Hu, Yaling; Feng, Yuyang; Li, Min; Bian, Zehua; Zhang, Jiwei; Qin, Yan; Qi, Xiaowei; Zhou, Leyuan; Fei, Bojian; Zou, Jian; Hua, Dong; Huang, Zhaohui

doi:10.1158/1078-0432.ccr-17-1283

Public

The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6

Published in Clinical Cancer Research • Sep 19, 2017

Authors:

Yuan Yin

Surui Yao

Yaling Hu

Abstract

Abstract Purpose: Tumor-associated macrophages (TAMs) are frequently associated with poor prognosis in human cancers. However, the effects of TAMs in colorectal cancer are contradictory. We therefore investigated the functions, mechanisms, and clinical significance of TAMs in colorectal cancer. Expe...

Subject

Colorectal cancer

Cancer research

Immune system

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