Safety and Efficacy of the Intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Patients With Heart Failure

Bartolucci, Jorge; Verdugo, Fernando; L. González, Paz; Larrea, Ricardo; Abarzúa, Ema; Goset, Carlos; Rojo, Pamela; Palma, Iván; Lamich, Rubén; Pedreros, Pablo; Valdivia, Gloria; M. Lopez, Valentina; Nazzal, Carolina; Alcayaga‐Miranda, Francisca; Cuenca, Jimena; Brobeck, Matthew; N. Patel, Amit; Figueroa, Fernando; Khoury, Maroun

doi:10.1161/circresaha.117.310712

Public

Safety and Efficacy of the Intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Patients With Heart Failure

Published in Circulation Research • Oct 3, 2017

Authors:

Jorge Bartolucci

Fernando Verdugo

Paz L. González

Abstract

Rationale: Umbilical cord–derived mesenchymal stem cells (UC-MSC) are easily accessible and expanded in vitro, possess distinct properties, and improve myocardial remodeling and function in experimental models of cardiovascular disease. Although bone marrow–derived mesenchymal stem cells have been p...

Subject

Ejection fraction

Mesenchymal stem cell

Medicine

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