Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials

G.F. Cleland, John; V Bunting, Karina; Flather, Marcus; G. Altman, Douglas; Holmes, Jane; J.S. Coats, Andrew; Manzano, Luís; J.V. McMurray, John; Ruschitzka, Frank; J. van Veldhuisen, Dirk; G. von Lueder, Thomas; Böhm, Michael; Andersson, Bert; Kjekshus, John; Packer, Milton; S. Rigby, Alan; Rosano, Giuseppe; Wedel, Hans; Hjalmarson, Åke; Wikstrand, John; Kotecha, Dipak; in Heart Failure Collaborative Group, Beta-blockers

doi:10.1093/eurheartj/ehx564

Public

Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials

Published in European Heart Journal • Sep 17, 2017

Authors:

John G.F. Cleland

Karina V Bunting

Marcus Flather

Abstract

Aims: Recent guidelines recommend that patients with heart failure and left ventricular ejection fraction (LVEF) 40-49% should be managed similar to LVEF ≥ 50%. We investigated the effect of beta-blockers according to LVEF in double-blind, randomized, placebo-controlled trials. Methods and results: ...

Subject

Medicine

Ejection fraction

Cardiology

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