miR-125b-5p functions as a tumor suppressor gene partially by regulating HMGA2 in esophageal squamous cell carcinoma

Mei, Li‐Li; Wang, Wenjun; Qiu, Yuntan; Xie, Xiufeng; Bai, Jie; Shi, Zhi‐Zhou

doi:10.1371/journal.pone.0185636

Public

miR-125b-5p functions as a tumor suppressor gene partially by regulating HMGA2 in esophageal squamous cell carcinoma

Published in PLoS ONE • Oct 2, 2017

Authors:

Li‐Li Mei

Wenjun Wang

Yuntan Qiu

Abstract

MicroRNAs (miRNAs) play important roles in the progression of human cancer including esophageal squamous cell carcinoma (ESCC). Although previous reports showed that miR-125b-5p was down-regulated in ESCC, the roles and mechanisms of loss of function of miR-125b-5p in ESCC were still unknown. Using ...

Subject

Gene knockdown

Ectopic expression

Cancer research

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