Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses

Yang, Guangbao; Xu, Ligeng; Chao, Yu; Xu, Jun; Sun, Xiaoqi; Wu, Yifan; Peng, Rui; Liu, Zhuang

doi:10.1038/s41467-017-01050-0

Public

Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses

Published in Nature Communications • Oct 6, 2017

Authors:

Guangbao Yang

Ligeng Xu

Yu Chao

Abstract

Abstract Herein, an intelligent biodegradable hollow manganese dioxide (H-MnO2) nano-platform is developed for not only tumor microenvironment (TME)-specific imaging and on-demand drug release, but also modulation of hypoxic TME to enhance cancer therapy, resulting in comprehensive effects favoring ...

Subject

Immune system

Tumor microenvironment

Nano-

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!