Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis

Schormair, Barbara; Zhao, Chen; Bell, Steven; Tilch, Erik; V. Salminen, Aaro; Pütz, Benno; Dauvilliers, Yves; Stefani, Ambra; Högl, Birgit; Poewe, Werner; Kemlink, David; Šonka, Karel; G. Bachmann, Cornelius; Paulus, Walter; Trenkwalder, Claudia; H. Oertel, Wolfgang; Hornyak, Magdolna; Teder‐Laving, Maris; Metspalu, Andres; M. Hadjigeorgiou, Georgios; Polo, Olli; Fietze, Ingo; A. Ross, Owen; K. Wszołek, Zbigniew; S. Butterworth, Adam; Soranzo, Nicole; H. Ouwehand, Willem; J. Roberts, David; Danesh, John; P. Allen, Richard; J. Earley, Christopher; G. Ondo, William; Xiong, Lan; Montplaisir, Jacques; Gan‐Or, Ziv; Perola, Markus; Vodička, Pavel; Dina, Christian; Franke, André; Tittmann, Lukas; F.R. Stewart, Alexandre; H. Shah, Svati; Gieger, Christian; Peters, Annette; A. Rouleau, Guy; Berger, Klaus; Oexle, Konrad; Di Angelantonio, Emanuele; A. Hinds, David; Müller‐Myhsok, Bertram; Winkelmann, Juliane; Balkau, Beverley; Ducimetière, Pierre; Eschwège, Eveline; Rancière, Fanny; Alhenc‐Gelas, François; Gallois, Yves; Girault, A; Fumeron, Frédéric; Marre, Michel; Roussel, Ronan; Bonnet, Fabrice; Bonnefond, Amélie; Cauchi, Stéphane; Froguel, Philippe; Cogneau, Joël; Born, C.; Cacès, E; Cailleau, M.; Lantieri, Olivier; Moreau, J.G.; Rakotozafy, F; Tichet, Jean; Vol, Sylviane; Agee, Michelle; Alipanahi, Babak; Auton, Adam; K. Bell, Robert; Bryc, Katarzyna; L. Elson, Sarah; Fontanillas, Pierre; A. Furlotte, Nicholas; A. Hinds, David; S. Hromatka, Bethann; E. Huber, Karen; Kleinman, Aaron; K. Litterman, Nadia; H. McIntyre, Matthew; L. Mountain, Joanna; A. M. Northover, Carrie; J. Pitts, Steven; Fah Sathirapongsasuti, J.; V. Sazonova, Olga; F. Shelton, Janie; Shringarpure, Suyash; Tian, Chao; Y. Tung, Joyce; Vacic, Vladimir; H. Wilson, Catherine

doi:10.1016/s1474-4422(17)30327-7

Public

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis

Published in The Lancet Neurology • Oct 13, 2017

Authors:

Barbara Schormair

Chen Zhao

Steven Bell

Abstract

BACKGROUND: Restless legs syndrome is a prevalent chronic neurological disorder with potentially severe mental and physical health consequences. Clearer understanding of the underlying pathophysiology is needed to improve treatment options. We did a meta-analysis of genome-wide association studies (...

Subject

Genome-wide association study

Meta-analysis

Odds ratio

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