Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma

Ducie, Jennifer; Dao, Fanny; Considine, Michael; Olvera, Narciso; A. Shaw, Patricia; J. Kurman, Robert; Shih, Ie-Ming; A. Soslow, Robert; Cope, Leslie; A. Levine, Douglas

doi:10.1038/s41467-017-01217-9

Public

Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma

Shared by NobleBlocks on Oct 17, 2017 • 12:00 AM UTC

Authors:

Jennifer Ducie

Fanny Dao

Michael Considine

Abstract

Abstract Many high-grade serous carcinomas (HGSCs) of the pelvis are thought to originate in the distal portion of the fallopian tube. Serous tubal intra-epithelial carcinoma (STIC) lesions are the putative precursor to HGSC and identifiable in ~ 50% of advanced stage cases. To better understand the...

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