An optimized SPE-LC-MS/MS method for antibiotics residue analysis in ground, surface and treated water samples by response surface methodology- central composite design

Mirzaei, Roya; Yunesian, Masud; Nasseri, Simin; Gholami, Mitra; Jalilzadeh, Esfandiyar; Shoeibi, Shahram; Shafieyan Bidshahi, Hooshang; Mesdaghinia, Alireza

doi:10.1186/s40201-017-0282-2

Public

An optimized SPE-LC-MS/MS method for antibiotics residue analysis in ground, surface and treated water samples by response surface methodology- central composite design

Published in Journal of Environmental Health Science and Engineering • Oct 17, 2017

Authors:

Roya Mirzaei

Masud Yunesian

Simin Nasseri

Abstract

BACKGROUND: Antibiotic residues are being constantly identified in environmental waters at low concentration. Growing concern has been expressed over the adverse environmental and human health effects even at low concentration. Hence, it is crucial to develop a multi-residues analytical method for a...

Subject

Chromatography

Central composite design

Response surface methodology

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