Dose-Response Association of CD8<sup>+</sup> Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer

L. Goode, Ellen; S. Block, Matthew; R. Kalli, Kimberly; A. Vierkant, Robert; Chen, Wenqian; C. Fogarty, Zachary; Gentry‐Maharaj, Aleksandra; Tołoczko, Aleksandra; Hein, Alexander; L. Bouligny, Aliecia; Jensen, Allan; Osório, Ana; D. Hartkopf, Andreas; Ryan, Andy; Chudecka-Głaz, Anita; M. Magliocco, Anthony; Hartmann, Arndt; Jung, Audrey; Gao, Bo; Y. Hernandez, Brenda; L. Fridley, Brooke; M. McCauley, Bryan; J. Kennedy, Catherine; Wang, Chen; Karpinskyj, Chloe; Bisinoto de Sousa, Christiani; Guimarães Tiezzi, Daniel; L. Wachter, David; Herpel, Esther; Taran, Florin‐Andrei; Modugno, Francesmary; Nelson, Gregg; Lubiński, Jan; Menkiszak, Janusz; Alsop, Jennifer; Lester, Jenny; García-Donás, Jesús; Nation, Jill; A. Hung, Jillian; Palacios, José; H. Rothstein, Joseph; L. Kelley, Joseph; Moreira de Andrade, Jurandyr; Robles-Díaz, Luis; P. Intermaggio, Maria; Widschwendter, Martin; W. Beckmann, Matthias; Ruebner, Matthias; Jimenez‐Liñan, Mercedes; Singh, Naveena; Oszurek, Oleg; R. Harnett, Paul; Rambau, Peter; Sinn, Hans‐Peter; Wagner, Philipp; Ghatage, Prafull; Sharma, Raghwa; P. Edwards, Robert; B. Ness, Roberta; Oršulić, Sandra; Y. Brucker, Sara; E. Johnatty, Sharon; A. Longacre, Teri; Eilber, Ursula; McGuire, Valerie; Sieh, Weiva; Natanzon, Yanina; Li, Zheng; S. Whittemore, Alice; DeFazio, Anna; Staebler, Annette; Y. Karlan, Beth; Blake Gilks, C.; D.L. Bowtell, David; Høgdall, Estrid; José Cândido dos Reis, Francisco; Steed, Helen; Campbell, Ian; Gronwald, Jacek; Benı́tez, Javier; M. Koziak, Jennifer; Chang‐Claude, Jenny; B. Moysich, Kirsten; E. Kelemen, Linda; S. Cook, Linda; T. Goodman, Marc; J. García, María; A. Fasching, Peter; Kommoss, Stefan; Deen, Suha; K. Kjær, Susanne; Menon, Usha; D. Brenton, James; D.P. Pharoah, Paul; Chenevix‐Trench, Georgia; G. Huntsman, David; J. Winham, Stacey; Köbel, Martin; J. Ramus, Susan

doi:10.1001/jamaoncol.2017.3290

Public

Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer

Published in JAMA Oncology • Oct 19, 2017

Authors:

Ellen L. Goode

Matthew S. Block

Kimberly R. Kalli

Abstract

Importance: Cytotoxic CD8+ tumor-infiltrating lymphocytes (TILs) participate in immune control of epithelial ovarian cancer; however, little is known about prognostic patterns of CD8+ TILs by histotype and in relation to other clinical factors. Objective: To define the prognostic role of CD8+ TILs i...

Subject

Medicine

Tumor-infiltrating lymphocytes

Serous fluid

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!