Nitrones and nucleobase-containing spiro-isoxazolidines derived from isatin and indanone: solvent-free microwave-assisted stereoselective synthesis and theoretical calculations

Maiuolo, Loredana; Merino, Pedro; Algieri, Vincenzo; Nardi, Mónica; Luisa Di Gioia, Maria; Russo, Beatrice; Delso, Ignacio; Antonio Tallarida, Matteo; De Nino, Antonio

doi:10.1039/c7ra09995a

Public

Nitrones and nucleobase-containing spiro-isoxazolidines derived from isatin and indanone: solvent-free microwave-assisted stereoselective synthesis and theoretical calculations

Shared by NobleBlocks on Jan 1, 2017 • 12:00 AM UTC

Authors:

Loredana Maiuolo

Pedro Merino

Vincenzo Algieri

Abstract

Here, we present a highly efficient approach to nucleobase-containing spiro-isoxazolidines with potential biological activity starting from isatinyl/indanyl nitrones.

Subject

Nucleobase

Isatin

Chemistry

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