Ectopic colonization of oral bacteria in the intestine drives T <sub>H</sub> 1 cell induction and inflammation

Atarashi, Koji; Suda, Wataru; Luo, Chengwei; Kawaguchi, Takaaki; Motoo, Iori; Narushima, Seiko; Kiguchi, Yuya; Yasuma-Mitobe, Keiko; Watanabe, Eiichiro; Tanoue, Takeshi; A. Thaiss, Christoph; Sato, Mayuko; Toyooka, Kiminori; Shehta Said, Heba; Yamagami, Hirokazu; A. Rice, Stuart; Gevers, Dirk; C. Johnson, Ryan; A. Segre, Julia; Chen, Kong; K. Kolls, Jay; Elinav, Eran; Morita, Hidetoshi; J. Xavier, Ramnik; Hattori, Masahira; Honda, Kenya

doi:10.1126/science.aan4526

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Ectopic colonization of oral bacteria in the intestine drives T H 1 cell induction and inflammation

Published in Science • Oct 19, 2017

Authors:

Koji Atarashi

Wataru Suda

Chengwei Luo

Abstract

Gut reasons to brush your teeth Some gut conditions, such as inflammatory bowel disease (IBD), ulcerative colitis, and Crohn's disease (CD), are associated with imbalances in the gut microbe community. The causes of these intractable diseases have been difficult to discern. Atarashi et al. took samp...

Subject

Colonization

Ulcerative colitis

Bacteria

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