Toll like receptors TLR1/2, TLR6 and MUC5B as binding interaction partners with cytostatic proline rich polypeptide 1 in human chondrosarcoma

Galoian, Karina; S. Abrahamyan, S.; Chailyan, Gor; Qureshi, Amir; Patel, Parthik; Metser, Gil; Moran, Alexandra; K. Sahakyan, I.; Tumasyan, Narine; Lee, Albert; K. Davtyan, Tigran; Chailyan, Samvel; A. Galoyan, Armen

doi:10.3892/ijo.2017.4199

Public

Toll like receptors TLR1/2, TLR6 and MUC5B as binding interaction partners with cytostatic proline rich polypeptide 1 in human chondrosarcoma

Published in International Journal of Oncology • Nov 9, 2017

Authors:

Karina Galoian

S. S. Abrahamyan

Gor Chailyan

Abstract

Metastatic chondrosarcoma is a bone malignancy not responsive to conventional therapies; new approaches and therapies are urgently needed. We have previously reported that mTORC1 inhibitor, antitumorigenic cytostatic proline rich polypeptide 1 (PRP-1), galarmin caused a significant upregulation of t...

Subject

Biology

Receptor

Cancer research

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