Emerging functions of the <scp>EGFR</scp> in cancer

Sigismund, Sara; Avanzato, Daniele; Lanzetti, Letizia

doi:10.1002/1878-0261.12155

Public

Emerging functions of the EGFR in cancer

Published in Molecular Oncology • Nov 10, 2017

Authors:

Sara Sigismund

Daniele Avanzato

Letizia Lanzetti

Abstract

The physiological function of the epidermal growth factor receptor (EGFR) is to regulate epithelial tissue development and homeostasis. In pathological settings, mostly in lung and breast cancer and in glioblastoma, the EGFR is a driver of tumorigenesis. Inappropriate activation of the EGFR in cance...

Subject

Cancer research

Cancer

Medicine

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