Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

David Mazer, C.; Whitlock, Richard; Fergusson, Dean; E. Hall, Judith; P. Belley‐Côté, Emilie; Connolly, Katherine; Khanykin, Boris; J. Gregory, Alexander; de Médicis, Étienne; McGuinness, Shay; Royse, Alistair; Martin Carrier, François; J. Young, Paul; Carlos Villar, Juan; P. Grocott, Hilary; D. Seeberger, Manfred; E. Fremes, Stephen; Lellouche, François; Syed, Summer; Byrne, Kelly; M. Bagshaw, Sean; Chih Hwang, Nian; Mehta, Chirag; Painter, Thomas; Royse, Colin; Verma, Subodh; M. T. Hare, Gregory; Cohen, Ashley; E. Thorpe, Kevin; Jüni, Peter; Shehata, Nadine

doi:10.1056/nejmoa1711818

Public

Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

Published in New England Journal of Medicine • Nov 12, 2017

Authors:

C. David Mazer

Richard Whitlock

Dean Fergusson

Abstract

BACKGROUND: The effect of a restrictive versus liberal red-cell transfusion strategy on clinical outcomes in patients undergoing cardiac surgery remains unclear. METHODS: In this multicenter, open-label, noninferiority trial, we randomly assigned 5243 adults undergoing cardiac surgery who had a Euro...

Subject

Medicine

Odds ratio

Confidence interval

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