GMSC-Derived Exosomes Combined with a Chitosan/Silk Hydrogel Sponge Accelerates Wound Healing in a Diabetic Rat Skin Defect Model

Shi, Quan; Qian, Zhiyong; Liu, Donghua; Sun, Jie; Wang, Xing; Liu, Hongchen; Xu, Juan; Guo, Ximin

doi:10.3389/fphys.2017.00904

Public

GMSC-Derived Exosomes Combined with a Chitosan/Silk Hydrogel Sponge Accelerates Wound Healing in a Diabetic Rat Skin Defect Model

Published in Frontiers in Physiology • Nov 7, 2017

Authors:

Quan Shi

Zhiyong Qian

Donghua Liu

Abstract

Background: Delayed wound healing in diabetic patients is one of the most challenging complications in clinical medicine, as it poses a greater risk of gangrene, amputation and even death. Therefore, a novel method to promote diabetic wound healing is of considerable interest at present. Previous st...

Subject

Wound healing

Mesenchymal stem cell

Microvesicles

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