Association Between Use of Thiopurines or Tumor Necrosis Factor Antagonists Alone or in Combination and Risk of Lymphoma in Patients With Inflammatory Bowel Disease

Lemaître, Magali; Kirchgesner, Julien; Rudnichi, A.; Carrat, Fabrice; Zureik, Mahmoud; Carbonnel, Franck; Dray‐Spira, Rosemary

doi:10.1001/jama.2017.16071

Public

Association Between Use of Thiopurines or Tumor Necrosis Factor Antagonists Alone or in Combination and Risk of Lymphoma in Patients With Inflammatory Bowel Disease

Published in JAMA • Nov 7, 2017

Authors:

Magali Lemaître

Julien Kirchgesner

A. Rudnichi

Abstract

IMPORTANCE: An increased risk of lymphoma has been reported among patients receiving thiopurines for inflammatory bowel disease (IBD). The risk of lymphoma associated with anti-tumor necrosis factor (TNF) agents either alone or in combination with thiopurines is uncertain. OBJECTIVE: To assess the r...

Subject

Medicine

Inflammatory bowel disease

Lymphoma

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