Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human

Nativel, Brice; David, C.; Giraud, Pierre; Meilhac, Olivier; Lefebvre d’Hellencourt, Christian; Viranaïcken, Wildriss; Robert Da Silva, Christine

doi:10.1038/s41598-017-16190-y

Public

Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human

Published in Scientific Reports • Nov 13, 2017

Authors:

Brice Nativel

C. David

Pierre Giraud

Abstract

Porphyromonas gingivalis is a key bacterium in chronic periodontitis, which is associated with several chronic inflammatory diseases. Lipopolysaccharides from P. gingivalis (Pg LPS) can activate multiple cell types via the production of pro-inflammatory cytokines. The receptors for Pg LPS have initi...

Subject

Porphyromonas gingivalis

TLR4

TLR2

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!