Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

J. Jansen, Willemijn; Ossenkoppele, Rik; M. Tijms, Betty; M. Fagan, Anne; Hansson, Oskar; E. Klunk, William; M. van der Flier, Wiesje; L. Villemagne, Victor; B. Frisoni, Giovanni; Fleisher, Adam; Lleó, Alberto; A. Mintun, Mark; Wallin, Anders; Engelborghs, Sebastiaan; L. Na, Duk; Chételat, Gaël; Luís Molinuevo, José; Landau, Susan; Mattsson, Niklas; Kornhuber, Johannes; Sabri, Osama; C. Rowe, Christopher; Parnetti, Lucilla; Popp, Julius; Fladby, Tormod; J. Jagust, William; Aalten, Pauline; Young Lee, Dong; Vandenberghe, Rik; R. Oliveira, Catarina; Kapaki, Elisabeth; Froelich, Lutz; Ivanoiu, Adrian; Gabryelewicz, Tomasz; M. Verbeek, Marcel; Sánchez‐Juan, Pascual; Hildebrandt, Helmut; Camus, Vincent; Zboch, Marzena; J. Brooks, David; Drzezga, Alexander; O. Rinne, Juha; B. Newberg, Andrew; de Mendonça, Alexandre; Sarazin, Marie; D. Rabinovici, Gil; Madsen, Karine; G. Kramberger, Milica; Nordberg, Agneta; Mok, Vincent; Mroczko, Barbara; A. Wolk, David; T. Meyer, Philipp; Tsolaki, Magda; Scheltens, Philip; R.J. Verhey, Frans; Jelle Visser, Pieter; Biomarker Study Group, Amyloid; Aarsland, Dag; Alcolea, Daniel; Alexander, M; S. Almdahl, Ina; E. Arnold, Steven; Baldeiras, Inês; Barthel, Henryk; N.M. van Berckel, Bart; Blennow, Kaj; A. van Buchem, Mark; Cavedo, Enrica; Chen, Kewei; Chipi, Elena; D. Cohen, Ann; Förster, Stefan; Fortea, Juan; Steen Frederiksen, Kristian; Freund‐Levi, Yvonne; Gkatzima, Olymbia; Forrest Gordon, Mark; Grimmer, Timo; Hampel, Harald; Hausner, Lucrezia; Hellwig, Sabine; Herukka, Sanna‐Kaisa; Johannsen, Peter; Klimkowicz‐Mrowiec, Aleksandra; Köhler, Sebastian; Koglin, Norman; Van Laere, Koen; J. de Leon, Mony; Lisetti, Viviana; Maier, Wolfgang; Marcusson, Jan; Meulenbroek, Olga; M. Møllergård, Hanne; C. Morris, John; Nordlund, Arto; Novak, Gerald; P. Paraskevas, George; Perera, Gayan; Peters, Oliver; H.G.B. Ramakers, Inez; Rami, Lorena; Rodríguez‐Rodríguez, Eloy; M. Roe, Catherine; Rot, Uroš; Rüther, Eckart; Santana, Isabel; Schröder, Johannes; Won Seo, Sang; Soininen, Hilkka; Spiru, Luiza; Stomrud, Erik; Struyfs, Hanne; E. Teunissen, Charlotte; J. B. Vos, Stephanie; Josephine Christine van Waalwijk van Doorn, Linda; Waldemar, Gunhild; K. Wallin, Åsa; Wiltfang, Jens; Zetterberg, Henrik

doi:10.1001/jamapsychiatry.2017.3391

Public

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

Published in JAMA Psychiatry • Nov 29, 2017

Authors:

Willemijn J. Jansen

Rik Ossenkoppele

Betty M. Tijms

Abstract

Importance: Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD). Understanding the association between amyloid aggregation and cognitive manifestation in persons without dementia is important for a better understanding of the course of AD and for the design of prevention trial...

Subject

Dementia

Association (psychology)

Cognition

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