Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study.

LJW, Bosch; Wit M, de; TV, Pham; VMH, Coupé; AC, Hiemstra; SR, Piersma; G, Oudgenoeg; GL, Scheffer; S, Mongera; Droste JT, Sive; FA, Oort; Turenhout ST, van; IB, Larbi; J, Louwagie; Criekinge W, van; der Hulst RWM, van; CJJ, Mulder; B, Carvalho; RJA, Fijneman; CR, Jimenez; GA, Meijer

doi:10.7326/m17-1068

Public

Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study.

Shared by NobleBlocks on Nov 21, 2017 • 12:00 AM UTC

Authors:

Bosch LJW

de Wit M

Pham TV

Abstract

Background The fecal immunochemical test (FIT) for detecting hemoglobin is used widely for noninvasive colorectal cancer (CRC) screening, but its sensitivity leaves room for improvement.Objective To identify novel protein biomarkers in stool that outperform or complement hemoglobin in detecting CRC ...

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