Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases

Albany, Costantine; H. Einhorn, Lawrence; Garbo, Lawrence; E. Boyd, Thomas; C. Josephson, Neil; R. Feldman, Darren

doi:10.1634/theoncologist.2017-0544

Public

Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases

Published in The Oncologist • Dec 8, 2017

Authors:

Costantine Albany

Lawrence H. Einhorn

Lawrence Garbo

Abstract

BACKGROUND: Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates. Expression of CD30 has been observed in testicular cancers, and patients with CD30-expressing embryonal carcinoma...

Subject

Medicine

Brentuximab vedotin

CD30

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