“Future-Proofing” Blood Processing for Measurement of Circulating miRNAs in Samples from Biobanks and Prospective Clinical Trials

J. Murray, Matthew; L. Watson, Hannah; Ward, Dawn; Bailey, Shivani; Ferraresso, Marta; C. Nicholson, James; J. Gnanapragasam, Vincent; Thomas, Benjamin; G. Scarpini, Cinzia; Coleman, Nicholas

doi:10.1158/1055-9965.epi-17-0657

Public

“Future-Proofing” Blood Processing for Measurement of Circulating miRNAs in Samples from Biobanks and Prospective Clinical Trials

Published in Cancer Epidemiology Biomarkers & Prevention • Dec 18, 2017

Authors:

Matthew J. Murray

Hannah L. Watson

Dawn Ward

Abstract

Abstract Background: Quantifying circulating nucleic acids is an important new approach to cancer diagnosis/monitoring. Methods: We compared the suitability of serum versus plasma for measuring miRNAs using qRT-PCR and assessed how preanalytic variables that can affect circulating tumor DNA (ctDNA) ...

Subject

Biobank

Clinical trial

Medicine

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