Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus

Hu, Ben; Zeng, Leiping; Yang, Xing‐Lou; Ge, Xing-Yi; Zhang, Wei; Li, Bei; Xie, Jiazheng; Shen, Xu-Rui; Zhang, Yun-Zhi; Wang, Ning; Luo, Dong-Sheng; Zheng, Xiao-Shuang; Wang, Mei-Niang; Daszak, Peter; Wang, Lin‐Fa; Cui, Jie; Shi, Zheng‐Li

doi:10.1371/journal.ppat.1006698

Public

Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus

Published in PLoS Pathogens • Nov 30, 2017

Authors:

Ben Hu

Leiping Zeng

Xing‐Lou Yang

Abstract

A large number of SARS-related coronaviruses (SARSr-CoV) have been detected in horseshoe bats since 2005 in different areas of China. However, these bat SARSr-CoVs show sequence differences from SARS coronavirus (SARS-CoV) in different genes (S, ORF8, ORF3, etc) and are considered unlikely to repres...

Subject

Biology

Coronavirus

Hypervariable region

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