Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma

Stupp, Roger; Taillibert, Sophie; A. Kanner, Andrew; L. Read, William; M. Steinberg, David; Lhermitte, Benoît; A. Toms, Steven; Idbaïh, Ahmed; S. Ahluwalia, Manmeet; Fink, Karen; Di Meco, Francesco; S. Lieberman, Frank; Zhu, Jay‐Jiguang; Stragliotto, Giuseppe; D. Tran, David; Brem, Steven; F. Hottinger, Andreas; D. Kirson, Eilon; Lavy-Shahaf, Gitit; Weinberg, Uri; Kim, Chae‐Yong; Paek, Sun-Ha; Nicholas, Garth; Bruna, Jordi; W. Hirte, Hal; Weller, Michael; Palti, Yoram; E. Hegi, Monika; Ram, Zvi

doi:10.1001/jama.2017.18718

Public

Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma

Published in JAMA • Dec 19, 2017

Authors:

Roger Stupp

Sophie Taillibert

Andrew A. Kanner

Abstract

Importance: Tumor-treating fields (TTFields) is an antimitotic treatment modality that interferes with glioblastoma cell division and organelle assembly by delivering low-intensity alternating electric fields to the tumor. Objective: To investigate whether TTFields improves progression-free and over...

Subject

Temozolomide

Medicine

Glioblastoma

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