Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic

P. Mukherjee, Sourav; R. Gliga, Anda; Lazzaretto, Beatrice; D. Brandner, Birgit; Fielden, Matthew; Vogt, Carmen; Newman, Leon; Filipe Rodrigues, Artur; Shao, Wenting; Fournier, Philip; S. Toprak, Muhammet; Star, Alexander; Kostarelos, Kostas; Bhattacharya, Kunal; Fadeel, Bengt

doi:10.1039/c7nr03552g

Public

Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic

Published in Nanoscale • Dec 18, 2017

Authors:

Sourav P. Mukherjee

Anda R. Gliga

Beatrice Lazzaretto

Abstract

Neutrophils were previously shown to digest oxidized carbon nanotubes through a myeloperoxidase (MPO)-dependent mechanism, and graphene oxide (GO) was found to undergo degradation when incubated with purified MPO, but there are no studies to date showing degradation of GO by neutrophils. Here we pro...

Subject

Degradation (telecommunications)

Graphene

Oxide

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