In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus

do Socorro da Silva Azevedo, Raimunda; Rodrigues de Sousa, Jorge; Tereza Ferreira de Araújo, Marialva; Jorge Martins Filho, Arnaldo; Nascimento de Alcântara, Bianca; Montenegro de Carvalho Araújo, Fernanda; Goretti Queiroz, Maria; Cecília Ribeiro Cruz, Ana; Helena Baldez Vasconcelos, Beatriz; Oliveira Chiang, Jannifer; Carício Martins, Lívia; Medeiros Neves Casseb, Lívia; V. da Silva, Eliana; Lima Carvalho, Valéria; Cristina Baldez Vasconcelos, Barbara; Guerreiro Rodrigues, Sueli; Silva de Oliveira, Consuelo; Antônio Simões Quaresma, Juarez; Fernando da Costa Vasconcelos, Pedro

doi:10.1038/s41598-017-17765-5

Public

In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus

Published in Scientific Reports • Jan 2, 2018

Authors:

Raimunda do Socorro da Silva Azevedo

Jorge Rodrigues de Sousa

Marialva Tereza Ferreira de Araújo

Abstract

Zika virus (ZIKV) has recently caused a pandemic disease, and many cases of ZIKV infection in pregnant women resulted in abortion, stillbirth, deaths and congenital defects including microcephaly, which now has been proposed as ZIKV congenital syndrome. This study aimed to investigate the in situ im...

Subject

Microcephaly

Zika virus

Pathology

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