Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation

Olliaro, Piero; Grögl, Max; Boni, Marina; M. Carvalho, Edgar; Chebli, Houda; Cissé, Mamoudou; Diro, Ermias; Cota, Gláucia; C. Erber, Astrid; Gadisa, Endalamaw; Handjani, Farhad; Khamesipour, Ali; Llanos‐Cuentas, Alejandro; López Carvajal, Liliana; Grout, Lise; Lmimouni, B.; Mokni, M.; Sami Nahzat, Mohammad; Ben Salah, Afif; Özbel, Yusuf; Miguel Pascale, Juan; Rizzo Molina, Nidia; Rode, Joelle; Adolfo Sierra Romero, Gustavo; A Ruiz-Postigo, José; Gore Saravia, Nancy; Soto, Jaime; Uzun, Soner; Mashayekhi, Vahid; Darío Vélez, Iván; Vogt, Florian; Zerpa, Olga; Arana, Byron

doi:10.1371/journal.pntd.0006141

Public

Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation

Published in PLoS neglected tropical diseases • Jan 12, 2018

Authors:

Piero Olliaro

Max Grögl

Marina Boni

Abstract

INTRODUCTION: Progress with the treatment of cutaneous leishmaniasis (CL) has been hampered by inconsistent methodologies used to assess treatment effects. A sizable number of trials conducted over the years has generated only weak evidence backing current treatment recommendations, as shown by syst...

Subject

Clinical trial

Standardization

Medical physics

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