PD-L1 expression is regulated by both DNA methylation and NF-kB during EMT signaling in non-small cell lung carcinoma

Asgarova, Afag; Asgarov, K.; Godet, Yann; Peixoto, Paul; Nadaradjane, Arulraj; Boyer‐Guittaut, Michaël; Galaine, Jeanne; Guenat, David; Mougey, Virginie; Perrard, Jérôme; Pallandre, Jean‐René; Bouard, Adeline; Balland, Jérémy; Tirole, Charline; Adotévi, Olivier; Hendrick, Elodie; Herfs, Michaël; Cartron, Pierre‐François; Borg, Christophe; Hervouet, Éric

doi:10.1080/2162402x.2017.1423170

Public

PD-L1 expression is regulated by both DNA methylation and NF-kB during EMT signaling in non-small cell lung carcinoma

Published in OncoImmunology • Jan 16, 2018

Authors:

Afag Asgarova

K. Asgarov

Yann Godet

Abstract

Tumor cells, which undergo Epithelial-mesenchymal transition (EMT) acquire increased capacities of proliferation, invasion and have the ability to generate metastases by escaping the immune system during their systemic migration. To escape the immune system, cancer cells may induce tolerance or resi...

Subject

Cancer research

Immune system

Fas ligand

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