Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with <sup>225</sup>Ac-PSMA-617: Swimmer-Plot Analysis Suggests Efficacy Regarding Duration of Tumor Control

Kratochwil, Clemens; Bruchertseifer, Frank; Rathke, Hendrik; Hohenfellner, Markus; L. Giesel, Frederik; Haberkorn, Uwe; Morgenstern, Aliyah

doi:10.2967/jnumed.117.203539

Public

Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with 225Ac-PSMA-617: Swimmer-Plot Analysis Suggests Efficacy Regarding Duration of Tumor Control

Published in Journal of Nuclear Medicine • Jan 11, 2018

Authors:

Clemens Kratochwil

Frank Bruchertseifer

Hendrik Rathke

Abstract

The aim of this evaluation was to identify the first indicators of efficacy for 225Ac-labeled prostate-specific membrane antigen (PSMA)–617 therapy in a retrospectively analyzed group of patients. Methods: Forty patients with metastatic castration-resistant prostate cancer were selected for treatmen...

Subject

Medicine

Prostate cancer

Glutamate carboxypeptidase II

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