FTO regulates the chemo‐radiotherapy resistance of cervical squamous cell carcinoma (CSCC) by targeting β‐catenin through mRNA demethylation

Zhou, Shun; Bai, Zhoulan; Xia, Di; Zhao, Zhijun; Zhao, Ren; Wang, Yanyang; Zhe, Hong

doi:10.1002/mc.22782

Public

FTO regulates the chemo‐radiotherapy resistance of cervical squamous cell carcinoma (CSCC) by targeting β‐catenin through mRNA demethylation

Published in Molecular Carcinogenesis • Jan 10, 2018

Authors:

Shun Zhou

Zhoulan Bai

Di Xia

Abstract

The role of N 6 ‐methyladenosine (m 6 A) demethylase fat mass and obesity‐associated protein (FTO) in the regulation of chemo‐radiotherapy resistance remains largely unknown. Here, we show that the mRNA level of FTO is elevated in cervical squamous cell carcinoma (CSCC) tissues when compared with re...

Subject

Biology

Cancer research

Demethylase

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