A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance

Chowdhary, Anuradha; Prakash, Anupam; Sharma, Cheshta; Kordalewska, Milena; Kumar, Anil; Sarma, Smita; Tarai, Bansidhar; Singh, Ashutosh; Upadhyaya, Gargi; Upadhyay, Shalini; Yadav, Priyanka; Kumar Singh, Pradeep; Khillan, Vikas; Sachdeva, Neelam; S. Perlin, David; F. Meis, Jacques

doi:10.1093/jac/dkx480

Public

A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance

Published in Journal of Antimicrobial Chemotherapy • Nov 22, 2017

Authors:

Anuradha Chowdhary

Anupam Prakash

Cheshta Sharma

Abstract

Background: Candida auris has emerged globally as an MDR nosocomial pathogen in ICU patients. Objectives: We studied the antifungal susceptibility of C. auris isolates (n = 350) from 10 hospitals in India collected over a period of 8 years. To investigate azole resistance, ERG11 gene sequencing and ...

Subject

Echinocandin

Candida auris

Fluconazole

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