Association of the Lung Immune Prognostic Index With Immune Checkpoint Inhibitor Outcomes in Patients With Advanced Non–Small Cell Lung Cancer

Mezquita, Laura; Auclin, Édouard; Ferrara, Roberto; Charrier, Mélinda; Remón, Jordi; Planchard, David; Ponce, Santiago; Paz Ares, Luis; Leroy, Laura; Audigier-Valette, Clarisse; Felip, Enriqueta; Zerón-Medina, Jorge; Garrido, Pilar; Brosseau, Solenn; Zalcman, Gérard; Mazières, Julien; Caramela, Caroline; Lahmar, J.; Adam, Julien; Chaput, Nathalie; Charles Soria, Jean; Besse, Benjamin

doi:10.1001/jamaoncol.2017.4771

Public

Association of the Lung Immune Prognostic Index With Immune Checkpoint Inhibitor Outcomes in Patients With Advanced Non–Small Cell Lung Cancer

Published in JAMA Oncology • Jan 11, 2018

Authors:

Laura Mezquita

Édouard Auclin

Roberto Ferrara

Abstract

IMPORTANCE: Derived neutrophils/(leukocytes minus neutrophils) ratio (dNLR) and lactate dehydrogenase (LDH) level have been correlated with immune checkpoint inhibitor (ICI) outcomes in patients with melanoma. OBJECTIVE: To determine whether pretreatment dNLR and LDH are associated with resistance t...

Subject

Medicine

Lung cancer

Internal medicine

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