Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells

Fan, Qing; Yang, Liang; Zhang, Xiaodong; Ma, Yingbo; Li, Yan; Dong, Lei; Zong, Zhi‐Hong; Hua, Xiangdong; Su, Dongming; Li, Hangyu; Liu, Jingang

doi:10.1186/s13046-018-0673-y

Public

Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells

Published in Journal of Experimental & Clinical Cancer Research • Jan 19, 2018

Authors:

Qing Fan

Liang Yang

Xiaodong Zhang

Abstract

Autophagy is a dynamic physiological process that can generate energy and nutrients for cell survival during stress. Autophagy can regulate the migration and invasive ability in cancer cells. However, the connection between autophagy and metabolism is unclear. Monocarboxylate transporter 1 (MCT1) pl...

Subject

Autophagy

Hepatocellular carcinoma

Wnt signaling pathway

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